Diabetes and Hypertension

Question: Discuss about theDiabetes and Hypertension. Answer: Introduction Most patients who have diabetes also suffer from hypertension. I have also been identified that there is some overlap between hypertension and diabetes in disease mechanism as well as in etiology. Some of the common pathways for these ailments are inflammation, obesity, insulin resistance, as well as oxidative stress. However, recent breakthroughs in knowledge of these pathways have availed new ways and perspectives in which the diseases can be managed. It has also been identified that people can embrace physical activities as one of the protective means against the disease. A critique of the article, Diabetes and Hypertension: Is there a standard Metabolic Pathway? by Bernard M. Y. And Cheung. Chao Li have been put to detail. Risk Factors for Atherosclerosis In the article, it has been indicated that both diabetes and hypertension are the two primary risk factors for atherosclerosis and the complication that associated with the disorder. According to Bernard and Cheung1, some of these complications are strokes and heart attacks. The article has also indicated that there is more than enough evidence that has shown that there is overlap between hypertension and diabetes. The evidence has also made it clear that there is also an excellent relation between the two concerning their disease mechanism and etiology. However, the article seems to avail shallow information regarding the risk factor for atherosclerosis. For example, according to Hu2, some of the major risk factors for this disorder are smoking, high blood pressure, unhealthy cholesterol levels in the blood, as well as high blood pressure. Kopelman, Caterson, and Dietz 3 argue that blood pressure is a phenomenon that can be grouped into two components, that is pulsatile and steady c omponent. Researchers have also demonstrated a relationship between cardiovascular risk factors and pulse pressure. Epidemiological readings have also indicated positive correlations between glucose metabolism impairment or smoking and pulse pressure. More contradicting information have been identified on the relationship between large artery stiffness and blood lipids. Also, Kopelman, Caterson, and Dietz 3, have indicated that atherosclerosis progresses more with increased blood pressure. In conclusion, Kopelman, Caterson, and Dietz3 argues that there is more than enough proof that blood pressure and other risk factors of the cardiovascular are directly associated. Causes of Hypertension and Diabetes The article also addresses the cause of hypertension and diabetes. For example, besides the genetic aspect of these disorders, environmental factors also influence whether a person will suffer from these diseases. According to Bernard and Cheung1, the environmental factors are composed of the lifestyle factors such as physical activities and diet, and also the period in the uterus. For instance, the latter environmental factor is comprised of aspects such as fetal malnutrition, high birth weight, and gestational diabetes. These factors have the ability to predispose the fetus to cardiometabolic syndrome later in the adulthood stage. Lifestyle factors, on the other hand, include high intake of alcohol, sodium, smoking, mental stress, lack of physical activities, and unsaturated fats. The article does not explain how these genetic, as well as environmental factors, influence a person from suffering from the disorders. For instance, according to Leslie 4, genetic factors play a great a role in determining the function and development of the major body systems as well as their susceptibility to the disorders. Congenital abnormalities and rare genetics that lead the kidney to develop abnormally are related to subsequent renal dysfunction occurrence. Hypertension and diabetes have considered being the most common causes of the end-stage renal disease (ESRD). Both renal and hypertension disorder prevalence vary among people of varying ethnic backgrounds, with the highest rates recorded among people of African descent and the Native Americans. According to Mohler Townsend 5, obesity, especially in the developing nations, is the most concerning condition that aids in the persistence and development of both hypertension and diabetes. Equally important, the fetal periods, particularly in the utero, influence the development of the utero structures. Unlike in the article where they have not mentioned what this condition is referred to as, Brenner, Rector Taal 6, refers to the state as developmental plasticity or fetal programming. Conclusion In conclusion, a critique of the article, Diabetes and Hypertension: Is there a Common Metabolic Pathway? by Bernard M. Y and Cheung. Chao Li have been put to detail. Some of the weaknesses of the article, such as not addressing the issue to detail have been analyzed and compared with other readings. For example, the article mentioned an environmental and genetic cause of diabetes and hypertension without explaining how these factors play a part. Compared with another reading, it has been observed that the article did not avail enough information regarding the causes. It is thus recommended that other readers consult other reading where information in the article appears vague. References Bernard, M. Y. Cheung. Chao Li. Diabetes and Hypertension: Is there a Common Metabolic Pathway? PDF. Hu, F. B. (2008). Obesity epidemiology. Oxford: Oxford University Press. Oxford ; New York : Oxford University Press Kopelman, P. G., Caterson, I., Dietz, W. (2009). Clinical Obesity in Adults and Children. Chichester: John Wiley Sons. Leslie, R. D. G. (2013). Causes of diabetes: Genetic and environmental factors. Chichester [England: J. Wiley. Mohler, E. R., Townsend, R. R. (2006). Advanced therapy in hypertension and vascular disease. Hamilton, Ont: B.C. Decker. Brenner, B. M., Rector, F. C., Taal, M. W. (2011). Brenner Rector's the kidney. Philadelphia, PA: Elsevier Saunders.